How Night Creams Can Help Fade Hyperpigmentation While You Sleep

Essential night creams are one of the best additions to your regular skin regimen. If you’ve ever asked how to remove dark spots caused by pimples overnight, night creams are your answer. They can aid your skin’s regeneration process while you catch up on your beauty sleep and wake you up to a radiant, even, spotless skin tone overnight. Here’s all you need to know about night skincare for pigmentation.

Keynotes:

• Your skin absorbs products better at night due to increased permeability and blood flow, making night creams effective in fading hyperpigmentation.
• Remove dark spots overnight with effective ingredients like Thiamidol (melanin regulator), Dexpanthenol (soothing agent), Hyaluronic Acid & Glycerin (hydration), and Licochalcone A (antioxidant).
• Follow a proper regimen to enhance results—cleanse, tone, apply serum, use a night cream, and finish with an under-eye cream for overnight dark spot reduction.

Your body follows a natural 24-hour circadian rhythm, which is crucial for understanding how to remove dark spots caused by pimples overnight. The circadian rhythm determines your sleep-wake cycles, hormonal cycles, and how your skin functions during different times of the day. It also changes how well skincare products work during different times of the day. Turns out that bedtime is one of the best times for skin cell regeneration and repair. Here’s why:

Skin's Nighttime Repair Process

Here are all the reasons why nighttime aids the efficacy of your essential night creams -

Increased Skin Absorption: The outermost layer of your skin is more permeable during the evening and night, which allows it to absorb skincare products better. This is why a moisturiser, topical serum, and other night skincare for pigmentation are more effective before bedtime.

Water Loss at Night: Due to more permeability, your skin loses more water at night. This is called transepidermal water loss (TEWL). This can leave you with dryness and itchiness, especially if you have dry skin conditions like eczema or dermatitis. Using an essential night cream with hydrating ingredients can help prevent this.

Higher Blood Flow to the Skin: Vasodilation occurs as you drift off into sleep at night. This means that your blood vessels expand at night and allow for more blood circulation in your face. This also helps deliver nutrients and repair damage, increasing the benefits of topical skincare and medicines.

Recovery from cell damage: After a day full of facing UV rays and oxidative stress, your skin finally gets a break at night. This is when the repair of these skin cells peaks at night and your skin’s ability to regenerate is at its strongest.

Hyperpigmentation happens when melanin (the pigment that gives skin its colour) builds up unevenly, leading to dark spots or patches. Night creams can help fade these spots by brightening, repairing, and hydrating the skin while you sleep.

1. Brightening and Evening Skin Tone

   Many fade-out, even skin tone night creams have antioxidants and skin-brightening ingredients like niacinamide, vitamin C, and dexpanthenol. These ingredients help you hydrate the skin, repair the skin barrier, and help your skin battle oxidative stress. Ingredients like Thiamidol can also help you fade pigmentation like acne marks, sun spots, and melasma with consistent use.

2. Accelerating Skin Cell Turnover

   At night, the skin's natural renewal process speeds up, allowing it to shed old, pigmented cells and produce fresh ones. Using night skincare for pigmentation with actives like Thiamidol helps you boost this process while restoring an even skin tone.

3. Targeting Inflammation and Redness

   Inflammation can make your acne marks and post-inflammatory hyperpigmentation worse. Using soothing agents like dexpanthenol helps you soothe the skin, reduce any redness or irritation, and prevent worsening of pigmentation.

4. Deep Hydration and Nourishment

   Hydration is essential for skin healing. Ingredients like hyaluronic acid, ceramides, and other humectants give your skin deep moisture, strengthening your skin barrier and keeping your skin plump. Maintaining your skin barrier also helps you stay protected from oxidative stress and water loss.

When choosing a night cream to target dark spots, look for these dermatologically backed ingredients:

Thiamidol

Well researched and patented, Thiamidol is a powerful melanin inhibitor that helps you reduce dark spots and other types of pigmentation while revealing a right, even skin tone. With a gentle formula, Thiamidol is suitable for all skin types and is an ideal ingredient if you’re trying to remove hyperpigmentation overnight.

Dexpanthenol

If you’re still asking how to remove dark spots caused by pimples overnight, a combination of dexpanthenol and Thiamidol is the answer. Derived from vitamin B5, dexpanthenol moisturises your skin, helps with anti-inflammatory benefits, and soothes any redness or irritation.

Hyaluronic Acid

As a humectant, hyaluronic acid attracts moisture from the atmosphere and uses it to replump your skin. It also helps your skin with elasticity and smooths over any fine lines. Hyaluronic acid is known for intensely hydrating your skin without making it feel weighed down. The essential night cream ingredient is suitable for all skin types.

Glycerin

Like hyaluronic acid, glycerin also works as a humectant that attracts moisture, prevents dryness and irritation, and keeps your skin hydrated during your beauty sleep.

Licochalcone A

A potent antioxidant that reduces inflammation and prevents redness-induced hyperpigmentation. This ingredient has anti-inflammatory, antioxidant, and detoxifying enzymes that protect the skin cells from oxidative stress. It can also soothe irritated skin and redness, calming your skin while you catch up on your beauty sleep.

If you’re wondering how to remove dark spots caused by pimples overnight, a proper skin regimen is the answer. Structure and layer your regimen properly to make sure that your night cream has the best effect.

Step 1: Cleanse

Start by washing your face gently to remove dirt, oil, and makeup. Use a cleansing gel with exfoliants to remove dead skin cells and unclog your pores.

We recommend: Dermopurifyer Tripe Effect Cleansing Gel

Step 2: Tone

Follow your cleansing gel with a hydrating and skin-balancing toner to remove any residual impurities. It also preps your skin for the products to come.

We recommend: Dermopurifyer Face Toner

Step 3: Serum

If you’re trying to remove dark spots overnight, invest in a good spot treatment. Start by applying a brightening serum with ingredients like Thiamidol and hyaluronic acid to target dark spots and maintain radiance.

We recommend: Anti-Pigment Dual Serum

Step 4: Night Cream

Allow your serum to completely sink in before you move on to the rest of your overnight treatment for dark spots. Once the serum sinks in, massage the night cream gently into your skin and give your skin night-long hydration. With Thiamidol and dexpanthenol, look for night creams that suit all skin types.

We recommend: Anti-Pigment Night Care

Step 5: Under Eye Cream

Layer your essential night cream with an under-eye cream with brightening agents to reduce dark circles and even out the delicate under-eye area.

We recommend: Anti-Pigment Dark Circle Eye Cream

Pro Tip: Use clean satin pillowcases and keep your head elevated while you sleep to maximise the benefits of your skincare.

Night creams are one of the most effective ways to remove dark spots overnight while you sleep. By using melanin-inhibiting, hydrating, and anti-inflammatory ingredients, essential night creams will help you wake up to radiant skin every morning.

1. How do you fade hyperpigmentation overnight?

   While it’s tough to fade hyperpigmentation in a single night, using night skincare for pigmentation consistently helps you restore a radiant, even, spotless skin tone.

2. Does night cream help with pigmentation?

   Yes. Essential night creams with ingredients like Thiamidol are one of the best ways to tackle pigmentation. Follow a consistent nighttime skincare routine, use a night cream, and get enough sleep for refreshed, radiant, spot-free skin.

3. Can you leave night cream on overnight?

   Yes. Use a night cream as the last layer of your bedtime skincare and leave it on overnight.

• Dimitrov, D., Salehi-Tabar, R., Anzulovich, A., & Jetten, A. M. (2019). Circadian clock and the epidermal barrier. International Journal of Molecular Sciences, 20(24), 6133.
• WebMD. (n.d.). Dexpanthenol topical: Uses, side effects, interactions, pictures, warnings & dosing. Retrieved March 31, 2025.
• NIVEA. (2023). Why is beauty sleep important? Retrieved March 31, 2025.
• Eucerin. (n.d.). Anti-Pigment Night Cream. Retrieved March 31, 2025.
• Healthline. (2023). The importance of beauty sleep for healthy skin. Retrieved March 31, 2025.